FZD1 Antikörper (AA 125-225) (Biotin)

Produktnummer ABIN7153180

Dieses Anti-FZD1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FZD1 in ELISA. Geeignet für Human.

Kurzübersicht für FZD1 Antikörper (AA 125-225) (Biotin) (ABIN7153180)

Target: FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FZD1 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-FZD1 Antikörper (Biotin)

Bindungsspezifität: AA 125-225

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Frizzled-10 protein (125-225AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu FZD1

Target: FZD1 (Fzd1) (Frizzled Family Receptor 1 (Fzd1))

Andere Bezeichnung: FZD1

Hintergrund:

Background: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.

Aliases: CD 350 antibody, CD 350 antigen antibody, CD350 antibody, Frizzled (Drosophila) homolog 10 antibody, Frizzled-10 antibody, FZ 10 antibody, Fz-10 antibody, FZ10 antibody, FZD 10 antibody, FZD10 antibody, FZD10_HUMAN antibody, FzE 7 antibody, FzE7 antibody, hFz 10 antibody, hFz10 antibody

UniProt: Q9ULW2

Pathways: WNT Signalweg, Asymmetric Protein Localization