FOXL2 Antikörper (AA 116-216) (Biotin)

Produktnummer ABIN7153063

Dieses Anti-FOXL2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FOXL2 in ELISA. Geeignet für Human.

Kurzübersicht für FOXL2 Antikörper (AA 116-216) (Biotin) (ABIN7153063)

Target: FOXL2 (Forkhead Box L2 (FOXL2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXL2 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-FOXL2 Antikörper (Biotin)

Bindungsspezifität: AA 116-216

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Forkhead box protein L2 protein (116-216AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu FOXL2

Target: FOXL2 (Forkhead Box L2 (FOXL2))

Andere Bezeichnung: FOXL2

Hintergrund:

Background: Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity). Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity). Is a regulator of CYP19 expression (By similarity). Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity). Is a transcriptional repressor of STAR. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2.

Aliases: Blepharophimosis antibody, Blepharophimosis epicanthus inversus and ptosis 1 antibody, Blepharophimosis epicanthus inversus and ptosis antibody, BPES 1 antibody, BPES antibody, BPES1 antibody, Epicanthus inversus and ptosis 1 antibody, Forkhead box L2 antibody, Forkhead box protein L2 antibody, Forkhead transcription factor FOXL2 antibody, FOX L2 antibody, FOXL 2 antibody, FOXL2 antibody, FOXL2_HUMAN antibody, PFRK antibody, PINTO antibody, PITUITARY FORKHEAD FACTOR antibody, POF 3 antibody, POF3 antibody

UniProt: P58012

Pathways: Nuclear Hormone Receptor Binding, Positive Regulation of Endopeptidase Activity