Filamin A Antikörper (AA 1234-1462) (Biotin)

Produktnummer ABIN7152945

Der Kaninchen Polyklonal Anti-Filamin A-Antikörper wurde für ELISA validiert. Er ist geeignet, Filamin A in Proben von Human zu detektieren.

Kurzübersicht für Filamin A Antikörper (AA 1234-1462) (Biotin) (ABIN7152945)

Target: Filamin A (FLNA) (Filamin A, alpha (FLNA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Filamin A Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-Filamin A Antikörper (Biotin)

Bindungsspezifität: AA 1234-1462

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Filamin-A protein (1234-1462AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Filamin A

Target: Filamin A (FLNA) (Filamin A, alpha (FLNA))

Andere Bezeichnung: FLNA

Hintergrund:

Background: Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface-localized furin, modulates its rate of internalization and directs its intracellular trafficking (By similarity). Involved in ciliogenesis. Plays a role in cell-cell contacts and adherens junctions during the development of blood vessels, heart and brain organs. Plays a role in platelets morphology through interaction with SYK that regulates ITAM- and ITAM-like-containing receptor signaling, resulting in by platelet cytoskeleton organization maintenance (By similarity).

Aliases: ABP 280 antibody, ABP-280 antibody, Actin-binding protein 280 antibody, Alpha filamin antibody, Alpha-filamin antibody, APBX antibody, CSBS antibody, CVD1 antibody, Endothelial actin binding protein antibody, Endothelial actin-binding protein antibody, Filamin 1 antibody, Filamin A alpha antibody, Filamin A antibody, Filamin-1 antibody, Filamin-A antibody, FLN antibody, FLN-A antibody, FLN1 antibody, FLNA antibody, FLNA_HUMAN antibody, FMD antibody, MNS antibody, NHBP antibody, Non muscle filamin antibody, Non-muscle filamin antibody, OPD antibody, OPD1 antibody, OPD2 antibody, XLVD antibody, XMVD antibody

UniProt: P21333

Pathways: T-Zell Rezeptor Signalweg, Maintenance of Protein Location