FCN1 Antikörper (AA 30-326)
Kurzübersicht für FCN1 Antikörper (AA 30-326) (ABIN7152931)
Target
Alle FCN1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 30-326
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Kreuzreaktivität
- Human
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Aufreinigung
- Antigen Affinity Purified
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Immunogen
- Recombinant Human Ficolin-1 protein (30-326AA)
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: IHC:1:20-1:200,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- FCN1 (Ficolin (Collagen/fibrinogen Domain Containing) 1 (FCN1))
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Andere Bezeichnung
- FCN1
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Hintergrund
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Background: Extracellular lectin functioning as a pattern-recognition receptor in innate immunity. Binds the sugar moieties of pathogen-associated molecular patterns (PAMPs) displayed on microbes and activates the lectin pathway of the complement system. May also activate monocytes through a G protein-coupled receptor, FFAR2, inducing the secretion of interleukin-8/IL-8 (PubMed:21037097). Binds preferentially to 9-O-acetylated 2-6-linked sialic acid derivatives and to various glycans containing sialic acid engaged in a 2-3 linkage.
Aliases: Collagen/fibrinogen domain containing protein 1 antibody, Collagen/fibrinogen domain-containing protein 1 antibody, Fcn1 antibody, FCN1_HUMAN antibody, FCNM antibody, ficolin (collagen/fibrinogen domain containing) 1 antibody, Ficolin 1 antibody, Ficolin A antibody, Ficolin alpha antibody, Ficolin-1 antibody, Ficolin-A antibody, Ficolin-alpha antibody, M ficolin antibody, M-ficolin antibody
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UniProt
- O00602
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Pathways
- Komplementsystem
Target
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