FGG Antikörper (AA 278-437) (FITC)

Produktnummer ABIN7152765

Der Kaninchen Polyklonal Anti-FGG-Antikörper wurde für validiert. Er ist geeignet, FGG in Proben von Human zu detektieren.

Kurzübersicht für FGG Antikörper (AA 278-437) (FITC) (ABIN7152765)

Target: FGG (Fibrinogen gamma Chain (FGG))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FGG Antikörper ist konjugiert mit FITC

Applikation: Bitte anfragen

Produktdetails anti-FGG Antikörper (FITC)

Bindungsspezifität: AA 278-437

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Fibrinogen gamma chain protein (278-437AA)

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu FGG

Target: FGG (Fibrinogen gamma Chain (FGG))

Andere Bezeichnung: FGG

Hintergrund:

Background: Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix. Has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.

Aliases: FGG antibody, FIBG_HUMAN antibody, Fibrinogen gamma chain antibody, Fibrinogen gamma polypeptide antibody, fibrinogen gamma-b chain antibody

UniProt: P02679