Fibrinogen beta Chain Antikörper (AA 346-465)
Kurzübersicht für Fibrinogen beta Chain Antikörper (AA 346-465) (ABIN7152759)
Target
Alle Fibrinogen beta Chain (FGB) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 346-465
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Kreuzreaktivität
- Human
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human Fibrinogen beta chain protein (346-465AA)
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: IHC:1:200-1:500,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Fibrinogen beta Chain (FGB)
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Andere Bezeichnung
- FGB
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Hintergrund
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Background: Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.
Aliases: Beta fibrinogen antibody, Epididymis Secretory Sperm Binding Protein Li 78p antibody, FGB antibody, FIBB_HUMAN antibody, Fibrinogen beta chain antibody, Fibrinogen, B Beta Polypeptide antibody, HEL-S-78p antibody
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UniProt
- P02675
Target
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