Fibrinogen beta Chain Antikörper (AA 346-465)

Produktnummer ABIN7152759

Der Kaninchen Polyklonal Anti-Fibrinogen beta Chain-Antikörper wurde für IHC und ELISA validiert. Er ist geeignet, Fibrinogen beta Chain in Proben von Human zu detektieren.

Kurzübersicht für Fibrinogen beta Chain Antikörper (AA 346-465) (ABIN7152759)

Target: Fibrinogen beta Chain (FGB)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Fibrinogen beta Chain Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Produktdetails anti-Fibrinogen beta Chain Antikörper

Bindungsspezifität: AA 346-465

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Fibrinogen beta chain protein (346-465AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:200-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Fibrinogen beta Chain

Target: Fibrinogen beta Chain (FGB)

Andere Bezeichnung: FGB

Hintergrund:

Background: Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.

Aliases: Beta fibrinogen antibody, Epididymis Secretory Sperm Binding Protein Li 78p antibody, FGB antibody, FIBB_HUMAN antibody, Fibrinogen beta chain antibody, Fibrinogen, B Beta Polypeptide antibody, HEL-S-78p antibody

UniProt: P02675