EIF3S1 Antikörper (AA 5-115)

Produktnummer ABIN7152166

Dieses Anti-EIF3S1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von EIF3S1 in ELISA und IHC. Geeignet für Human.

Kurzübersicht für EIF3S1 Antikörper (AA 5-115) (ABIN7152166)

Target: EIF3S1 (Eukaryotic Translation Initiation Factor 3 Subunit J (EIF3S1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF3S1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-EIF3S1 Antikörper

Bindungsspezifität: AA 5-115

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Eukaryotic translation initiation factor 3 subunit J protein (5-115AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu EIF3S1

Target: EIF3S1 (Eukaryotic Translation Initiation Factor 3 Subunit J (EIF3S1))

Andere Bezeichnung: EIF3J

Hintergrund:

Background: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. This subunit binds directly within the mRNA entry channel of the 40S ribosome to the aminoacyl (A) site. It may regulate the interaction between the 43S PIC and mRNA.

Aliases: eIF 3 alpha antibody, eIF-3-alpha antibody, eIF3 alpha antibody, eIF3 p35 antibody, eIF3j antibody, EIF3J_HUMAN antibody, EIF3S 1 antibody, EIF3S1 antibody, Eukaryotic translation initiation factor 3 subunit 1 antibody, Eukaryotic translation initiation factor 3 subunit J antibody, Eukaryotic translation initiation factor 3, subunit 1 (alpha, 35kD) antibody, Eukaryotic translation initiation factor 3, subunit 1 alpha, 35kD antibody

UniProt: O75822

Pathways: Ribonucleoprotein Complex Subunit Organization