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EIF3S1 Antikörper (Internal Region)

EIF3S1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6261484
  • Target Alle EIF3S1 Antikörper anzeigen
    EIF3S1 (Eukaryotic Translation Initiation Factor 3 Subunit J (EIF3S1))
    Bindungsspezifität
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 33
    • 18
    • 15
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 30
    • 3
    Kaninchen
    Klonalität
    • 33
    Polyklonal
    Konjugat
    • 19
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser EIF3S1 Antikörper ist unkonjugiert
    Applikation
    • 20
    • 10
    • 6
    • 5
    • 4
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    EIF3J Antibody detects endogenous levels of total EIF3J.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human EIF3J, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product EIF3S1 Primärantikörper
  • Applikationshinweise
    WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    EIF3S1 (Eukaryotic Translation Initiation Factor 3 Subunit J (EIF3S1))
    Andere Bezeichnung
    EIF3J (EIF3S1 Produkte)
    Synonyme
    GB12381 antikoerper, An18g06260 antikoerper, AO090003000054 antikoerper, EIF3S1 antikoerper, eIF3j antikoerper, eIF3-alpha antikoerper, eIF3-p35 antikoerper, Eif3s1 antikoerper, eif3s1 antikoerper, 1810016I04Rik antikoerper, 2700079K05Rik antikoerper, AA409117 antikoerper, AA409446 antikoerper, C78575 antikoerper, Eif3j antikoerper, Eif3j-1 antikoerper, Eif3j-2 antikoerper, Eif3j2 antikoerper, eIF-3-alpha-A antikoerper, eIF-3-alpha-B antikoerper, eIF3j-A antikoerper, eIF3j-B antikoerper, eukaryotic translation initiation factor 3 subunit J antikoerper, eukaryotic translation initiation factor 3, subunit J antikoerper, Eukaryotic translation initiation factor 3 subunit J antikoerper, eukaryotic translation initiation factor 3 subunit 1 antikoerper, eukaryotic translation initiation factor 3 subunit J S homeolog antikoerper, eukaryotic translation initiation factor 3, subunit J1 antikoerper, LOC409796 antikoerper, ANI_1_830164 antikoerper, AOR_1_94154 antikoerper, Eif3j antikoerper, EIF3J antikoerper, eif3j antikoerper, LOC733089 antikoerper, eif3j.S antikoerper, Eif3j1 antikoerper
    Hintergrund

    Description: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773).

    Gene: EIF3J

    Molekulargewicht
    29 kDa
    Gen-ID
    8669
    UniProt
    O75822
    Pathways
    Ribonucleoprotein Complex Subunit Organization
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