ERO1LB Antikörper (AA 101-400) (FITC)

Produktnummer ABIN7152006

Der Kaninchen Polyklonal Anti-ERO1LB-Antikörper wurde für validiert. Er ist geeignet, ERO1LB in Proben von Human zu detektieren.

Kurzübersicht für ERO1LB Antikörper (AA 101-400) (FITC) (ABIN7152006)

Target: ERO1LB (ERO1-Like beta (ERO1LB))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERO1LB Antikörper ist konjugiert mit FITC

Applikation: Bitte anfragen

Produktdetails anti-ERO1LB Antikörper (FITC)

Bindungsspezifität: AA 101-400

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human ERO1-like protein beta protein (101-400AA)

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ERO1LB

Target: ERO1LB (ERO1-Like beta (ERO1LB))

Andere Bezeichnung: ERO1B

Hintergrund:

Background: Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Other protein disulfide isomerase family members can also be reoxidized, but at lower rates compared to P4HB, including PDIA2 (50 % of P4HB reoxidation rate), as well as PDIA3, PDIA4, PDIA6 and NXNDC12 (<10 %). Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. May be involved in oxidative proinsulin folding in pancreatic cells, hence may play a role in glucose homeostasis.

Aliases: Endoplasmic oxidoreductin-1-like protein B antibody, Endoplasmic reticulum oxidoreductin-1-like protein B antibody, ERO1, S. cerevisiae, homolog of, beta antibody, ERO1-L-beta antibody, ERO1-like beta (S. cerevisiae) antibody, ERO1-like protein beta antibody, ERO1B_HUMAN antibody, Ero1lb antibody, Oxidoreductin-1-L-beta antibody

UniProt: Q86YB8

Pathways: SARS-CoV-2 Protein Interaktom