ERO1L Antikörper (AA 24-260)

Produktnummer ABIN7152002

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ERO1L in WB, ELISA und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für ERO1L Antikörper (AA 24-260) (ABIN7152002)

Target: ERO1L (ERO1-Like Protein alpha (ERO1L))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERO1L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-ERO1L Antikörper

Bindungsspezifität: AA 24-260

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human ERO1-like protein alpha protein (24-260AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ERO1L

Target: ERO1L (ERO1-Like Protein alpha (ERO1L))

Andere Bezeichnung: ERO1A

Hintergrund:

Background: Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. Required for the proper folding of immunoglobulins. Involved in the release of the unfolded cholera toxin from reduced P4HB/PDI in case of infection by V.cholerae, thereby playing a role in retrotranslocation of the toxin. Plays an important role in ER stress-induced, CHOP-dependent apoptosis by activating the inositol 1,4,5-trisphosphate receptor IP3R1.

Aliases: Endoplasmic oxidoreductin 1 like protein antibody, Endoplasmic oxidoreductin-1-like protein antibody, Endoplasmic reticulum oxidoreductase 1 alpha antibody, Endoplasmic reticulum oxidoreductin 1-like antibody, ERO1 alpha antibody, ERO1 L antibody, ERO1 Lalpha antibody, ERO1 like protein alpha antibody, ERO1-alpha antibody, ERO1-L antibody, ERO1-L-alpha antibody, ERO1-like (S. cerevisiae) antibody, ERO1-like alpha antibody, ERO1-like protein alpha antibody, ERO1-like, S. cerevisiae, homolog of, alpha antibody, ERO1A antibody, ERO1A_HUMAN antibody, ERO1L antibody, ERO1LA antibody, Oxidoreductin 1 Lalpha antibody, Oxidoreductin-1-L-alpha antibody, PRO865 antibody, UNQ434 antibody

UniProt: Q96HE7

Pathways: Peptide Hormone Metabolism, ER-Nucleus Signaling, Brown Fat Cell Differentiation