EDEM1 Antikörper (AA 46-128)
Kurzübersicht für EDEM1 Antikörper (AA 46-128) (ABIN7151970)
Target
Alle EDEM1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 46-128
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Verwendungszweck
- EDEM1 Antibody
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Aufreinigung
- Protein G purified
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Reinheit
- >95 %
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Immunogen
- Recombinant Human ER degradation-enhancing alpha-mannosidase-like protein 1 protein (46-128AA)
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Isotyp
- IgG
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anti-ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1) (AA 559-656) antibody
EDEM1 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 2D3 unconjugated
anti-ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1) (C-Term) antibodyEDEM1 Reaktivität: Human, Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1) (AA 146-195) antibodyEDEM1 Reaktivität: Human, Maus, Rind (Kuh), Kaninchen, Affe, Schwein, Meerschweinchen, Hamster WB Wirt: Kaninchen Polyclonal unconjugated
anti-ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1) (N-Term) antibodyEDEM1 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- EDEM1 (ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1))
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Andere Bezeichnung
- EDEM1
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Hintergrund
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Background: Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It has low mannosidase activity, catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2.
Aliases: EDEM1 antibody, EDEM antibody, KIAA0212ER degradation-enhancing alpha-mannosidase-like protein 1 antibody
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UniProt
- Q92611
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Pathways
- ER-Nucleus Signaling
Target
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