Ephrin B1 Antikörper (AA 28-237)

Produktnummer ABIN7151877

Der Kaninchen Polyklonal Anti-Ephrin B1-Antikörper wurde für ELISA und IHC validiert. Er ist geeignet, Ephrin B1 in Proben von Human zu detektieren.

Kurzübersicht für Ephrin B1 Antikörper (AA 28-237) (ABIN7151877)

Target: Ephrin B1 (EFNB1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Ephrin B1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-Ephrin B1 Antikörper

Bindungsspezifität: AA 28-237

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Ephrin-B1 protein (28-237AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Ephrin B1

Target: Ephrin B1 (EFNB1)

Andere Bezeichnung: EFNB1

Hintergrund:

Background: Binds to the receptor tyrosine kinases EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons. Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to the receptor tyrosine kinases EPHB3 (preferred), EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons.

Aliases: CFND antibody, CFNS antibody, Craniofrontonasal syndrome (craniofrontonasal dysplasia) antibody, EFL 3 antibody, EFL-3 antibody, EFL3 antibody, EFNB1 antibody, EFNB1_HUMAN antibody, Elk L antibody, ELK ligand antibody, ELK-L antibody, Eph related receptor tyrosine kinase ligand 2 antibody, EPH-related receptor tyrosine kinase ligand 2 antibody, Ephrin-B1 antibody, EPLG2 antibody, LERK 2 antibody, LERK-2 antibody, LERK2 antibody, Ligand of eph related kinase 2 antibody, MGC8782 antibody

UniProt: P98172

Pathways: RTK Signalweg