EPH Receptor B3 Antikörper (AA 261-390) (FITC)

Produktnummer ABIN7151866

Dieses Anti-EPH Receptor B3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von EPH Receptor B3 in . Geeignet für Human.

Kurzübersicht für EPH Receptor B3 Antikörper (AA 261-390) (FITC) (ABIN7151866)

Target: EPH Receptor B3 (EPHB3)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPH Receptor B3 Antikörper ist konjugiert mit FITC

Applikation: Bitte anfragen

Produktdetails anti-EPH Receptor B3 Antikörper (FITC)

Bindungsspezifität: AA 261-390

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Ephrin type-B receptor 3 protein (261-390AA)

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu EPH Receptor B3

Target: EPH Receptor B3 (EPHB3)

Andere Bezeichnung: EPHB3

Hintergrund:

Background: Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Generally has an overlapping and redundant function with EPHB2. Like EPHB2, functions in axon guidance during development regulating for instance the neurons forming the corpus callosum and the anterior commissure, 2 major interhemispheric connections between the temporal lobes of the cerebral cortex. In addition to its role in axon guidance plays also an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and the formation of excitatory synapses. Controls other aspects of development through regulation of cell migration and positioning. This includes angiogenesis, palate development and thymic epithelium development for instance. Forward and reverse signaling through the EFNB2/EPHB3 complex also regulate migration and adhesion of cells that tubularize the urethra and septate the cloaca. Finally, plays an important role in intestinal epithelium differentiation segregating progenitor from differentiated cells in the crypt.

Aliases: Cek10 antibody, EK2 antibody, Embryonic kinase 2 antibody, EPH Like Tyrosine Kinase 2 antibody, EPH receptor B3 antibody, EPH-like kinase 2 antibody, ephb3 antibody, EPHB3_HUMAN antibody, Ephrin receptor EphB3 antibody, Ephrin type B receptor 3 antibody, Ephrin type-B receptor 3 antibody, ETK2 antibody, hEK2 antibody, Human Embryo Kinase 2 antibody, Mdk5 antibody, Sek4 antibody, TYRO6 antibody, Tyrosine protein kinase receptor HEK2 antibody, Tyrosine protein kinase TYRO6 antibody, Tyrosine-protein kinase TYRO6 antibody

UniProt: P54753

Pathways: RTK Signalweg