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EPH Receptor A8 Antikörper (AA 45-249) (Biotin)

This anti-EPH Receptor A8 antibody (ABIN7151856) is a Rabbit Polyclonal antibody detecting EPH Receptor A8 in ELISA. Suitable for Human.
Produktnummer ABIN7151856

Kurzübersicht für EPH Receptor A8 Antikörper (AA 45-249) (Biotin) (ABIN7151856)

Target

Alle EPH Receptor A8 (EPHA8) Antikörper anzeigen
EPH Receptor A8 (EPHA8)

Reaktivität

  • 9
  • 2
  • 1
Human

Wirt

  • 7
  • 2
Kaninchen

Klonalität

  • 7
  • 2
Polyklonal

Konjugat

  • 6
  • 2
  • 1
Dieser EPH Receptor A8 Antikörper ist konjugiert mit Biotin

Applikation

  • 7
  • 5
  • 1
  • 1
ELISA
  • Bindungsspezifität

    • 3
    • 2
    AA 45-249

    Kreuzreaktivität

    Human

    Aufreinigung

    Antigen Affinity Purified

    Immunogen

    Recombinant Human Ephrin type-A receptor 8 protein (45-249AA)

    Isotyp

    IgG
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    EPH Receptor A8 (EPHA8)

    Andere Bezeichnung

    EPHA8

    Hintergrund

    Background: Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. The GPI-anchored ephrin-A EFNA2, EFNA3, and EFNA5 are able to activate EPHA8 through phosphorylation. With EFNA5 may regulate integrin-mediated cell adhesion and migration on fibronectin substrate but also neurite outgrowth. During development of the nervous system plays also a role in axon guidance. Downstream effectors of the EPHA8 signaling pathway include FYN which promotes cell adhesion upon activation by EPHA8 and the MAP kinases in the stimulation of neurite outgrowth (By similarity).

    Aliases: EPHA8 antibody, EEK antibody, HEK3 antibody, KIAA1459Ephrin type-A receptor 8 antibody, EC 2.7.10.1 antibody, EPH- and ELK-related kinase antibody, EPH-like kinase 3 antibody, EK3 antibody, hEK3 antibody, Tyrosine-protein kinase receptor EEK antibody

    UniProt

    P29322

    Pathways

    RTK Signalweg
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