ERP29 Antikörper (AA 40-251) (FITC)

Produktnummer ABIN7151685

Der Kaninchen Polyklonal Anti-ERP29-Antikörper wurde für validiert. Er ist geeignet, ERP29 in Proben von Human zu detektieren.

Kurzübersicht für ERP29 Antikörper (AA 40-251) (FITC) (ABIN7151685)

Target: ERP29 (Endoplasmic Reticulum Protein 29 (ERP29))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERP29 Antikörper ist konjugiert mit FITC

Applikation: Bitte anfragen

Produktdetails anti-ERP29 Antikörper (FITC)

Bindungsspezifität: AA 40-251

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Endoplasmic reticulum resident protein 29 protein (40-251AA)

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ERP29

Target: ERP29 (Endoplasmic Reticulum Protein 29 (ERP29))

Andere Bezeichnung: ERP29

Hintergrund:

Background: Proper protein folding and post-translational modifications are essential for secretory protein export out of the endoplasmic reticulum. This task is accomplished by chaperone proteins such as protein disulfide isomerase (PDI), GRP94, and BiP. A recently characterized protein, designated ERp29, is closely related to these chaperone proteins and appears to be upregulated during ER stress conditions. ERp29 is a soluble 259-residue protein that is localized to the lumen of the endoplasmic reticulum in all mammalian cells. Research has shown that there are two primary domains within ERp29. The first is the C-terminal region that is a novel, all helical, fold that is most likely involved with ERp29 retention to the ER. The second is the N-terminal region that resembles that of PDI's thioredoxin module. The protein shows sequence similarity to the protein disulfide isomerase family. However, it lacks the thioredoxin motif characteristic of this family, suggesting that this protein does not function as a disulfide isomerase. The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER.

Aliases: ERP29 antibody, C12orf8 antibody, ERP28Endoplasmic reticulum resident protein 29 antibody, ERp29 antibody, Endoplasmic reticulum resident protein 28 antibody, ERp28 antibody, Endoplasmic reticulum resident protein 31 antibody, ERp31 antibody

UniProt: P30040