ERP29 Antikörper (AA 40-251)

Produktnummer ABIN7151681

Produktdetails anti-ERP29 Antikörper

Target: ERP29 (Endoplasmic Reticulum Protein 29 (ERP29))

Bindungsspezifität: AA 40-251

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERP29 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Endoplasmic reticulum resident protein 29 protein (40-251AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ERP29

Target: ERP29 (Endoplasmic Reticulum Protein 29 (ERP29))

Andere Bezeichnung: ERP29 (ERP29 Produkte)

Synonyme: C12orf8 antikoerper, ERp28 antikoerper, ERp31 antikoerper, PDI-DB antikoerper, PDIA9 antikoerper, 1200015M03Rik antikoerper, 2810446M09Rik antikoerper, AW209030 antikoerper, Erp28 antikoerper, Erp31 antikoerper, PDI-Db antikoerper, endoplasmic reticulum protein 29 antikoerper, ERP29 antikoerper, Erp29 antikoerper

Hintergrund:

Background: Proper protein folding and post-translational modifications are essential for secretory protein export out of the endoplasmic reticulum. This task is accomplished by chaperone proteins such as protein disulfide isomerase (PDI), GRP94, and BiP. A recently characterized protein, designated ERp29, is closely related to these chaperone proteins and appears to be upregulated during ER stress conditions. ERp29 is a soluble 259-residue protein that is localized to the lumen of the endoplasmic reticulum in all mammalian cells. Research has shown that there are two primary domains within ERp29. The first is the C-terminal region that is a novel, all helical, fold that is most likely involved with ERp29 retention to the ER. The second is the N-terminal region that resembles that of PDI's thioredoxin module. The protein shows sequence similarity to the protein disulfide isomerase family. However, it lacks the thioredoxin motif characteristic of this family, suggesting that this protein does not function as a disulfide isomerase. The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER.

Aliases: ERP29 antibody, C12orf8 antibody, ERP28Endoplasmic reticulum resident protein 29 antibody, ERp29 antibody, Endoplasmic reticulum resident protein 28 antibody, ERp28 antibody, Endoplasmic reticulum resident protein 31 antibody, ERp31 antibody

UniProt: P30040