UBR1 Antikörper (AA 722-862) (HRP)
Kurzübersicht für UBR1 Antikörper (AA 722-862) (HRP) (ABIN7151296)
Target
Alle UBR1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 722-862
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Kreuzreaktivität
- Human
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human E3 ubiquitin-protein ligase UBR1 protein (722-862AA)
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- UBR1 (Ubiquitin Protein Ligase E3 Component N-Recognin 1 (UBR1))
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Andere Bezeichnung
- UBR1
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Hintergrund
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Background: E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. May be involved in pancreatic homeostasis. Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth.
Aliases: E3 ubiquitin-protein ligase UBR1 antibody, JBS antibody, N-recognin-1 antibody, ubiquitin protein ligase E3 component n-recognin 1 antibody, Ubiquitin-protein ligase E3-alpha-1 antibody, Ubiquitin-protein ligase E3-alpha-I antibody, UBR1 antibody, UBR1_HUMAN antibody
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UniProt
- Q8IWV7
Target
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