RNF43 Antikörper (AA 566-697)
Kurzübersicht für RNF43 Antikörper (AA 566-697) (ABIN7151198)
Target
Alle RNF43 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 566-697
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Kreuzreaktivität
- Human
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human E3 ubiquitin-protein ligase RNF43 protein (566-697AA)
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: IHC:1:500-1:1000,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- RNF43 (Ring Finger Protein 43 (RNF43))
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Andere Bezeichnung
- RNF43
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Hintergrund
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Background: E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone.
Aliases: RNF43 antibody, E3 ubiquitin-protein ligase RNF43 antibody, EC 2.3.2.27 antibody, RING finger protein 43 antibody, RING-type E3 ubiquitin transferase RNF43 antibody
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UniProt
- Q68DV7
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Pathways
- WNT Signalweg
Target
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