MYLIP Antikörper (AA 266-445)
Kurzübersicht für MYLIP Antikörper (AA 266-445) (ABIN7151076)
Target
Alle MYLIP Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 266-445
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Kreuzreaktivität
- Human
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Aufreinigung
- Antigen Affinity Purified
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Immunogen
- Recombinant Human E3 ubiquitin-protein ligase MYLIP protein (266-445AA)
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Isotyp
- IgG
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anti-Myosin Regulatory Light Chain Interacting Protein (MYLIP) (AA 111-139) antibody
MYLIP Reaktivität: Human, Maus, Ratte WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB18661 unconjugated
anti-Myosin Regulatory Light Chain Interacting Protein (MYLIP) (AA 266-445) antibodyMYLIP Reaktivität: Human WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Myosin Regulatory Light Chain Interacting Protein (MYLIP) (Internal Region) antibodyMYLIP Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Myosin Regulatory Light Chain Interacting Protein (MYLIP) (Internal Region) antibodyMYLIP Reaktivität: Human, Maus, Ratte WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Myosin Regulatory Light Chain Interacting Protein (MYLIP) (AA 65-103) antibodyMYLIP Reaktivität: Human, Maus, Ratte WB, IF (p), IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Myosin Regulatory Light Chain Interacting Protein (MYLIP) (AA 440-475), (C-Term) antibodyMYLIP Reaktivität: Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal RB47051 unconjugated
anti-Myosin Regulatory Light Chain Interacting Protein (MYLIP) (AA 1-445) antibodyMYLIP Reaktivität: Human ELISA Wirt: Maus Monoclonal 3C10 unconjugated
anti-Myosin Regulatory Light Chain Interacting Protein (MYLIP) (AA 360-409) antibodyMYLIP Reaktivität: Human, Maus, Ratte, Fledermaus, Schwein WB Wirt: Kaninchen Polyclonal unconjugated
anti-Myosin Regulatory Light Chain Interacting Protein (MYLIP) (Center) antibodyMYLIP Reaktivität: Human, Maus, Rind (Kuh), Affe WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Myosin Regulatory Light Chain Interacting Protein (MYLIP) (AA 161-210) antibodyMYLIP Reaktivität: Human, Maus, Ratte WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Recommended dilution: IHC:1:20-1:200,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MYLIP (Myosin Regulatory Light Chain Interacting Protein (MYLIP))
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Andere Bezeichnung
- MYLIP
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Hintergrund
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Background: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC), LDLR, VLDLR and LRP8. Activity depends on E2 enzymes of the UBE2D family. Proteasomal degradation of MRLC leads to inhibit neurite outgrowth in presence of NGF by counteracting the stabilization of MRLC by saposin-like protein (CNPY2/MSAP) and reducing CNPY2-stimulated neurite outgrowth. Acts as a sterol-dependent inhibitor of cellular cholesterol uptake by mediating ubiquitination and subsequent degradation of LDLR.
Aliases: BM-023 antibody, BZF1 antibody, E3 ubiquitin protein ligase MYLIP antibody, E3 ubiquitin-protein ligase MYLIP antibody, Idol antibody, Inducible degrader of the LDL-receptor antibody, Lipoprotein receptor antibody, MIR antibody, MYLIP antibody, MYLIP_HUMAN antibody, Myosin regulatory light chain interacting protein antibody, PP5242 antibody
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UniProt
- Q8WY64
Target
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