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MYLIP Antikörper (AA 266-445)

MYLIP Reaktivität: Human WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7151077
  • Target Alle MYLIP Antikörper anzeigen
    MYLIP (Myosin Regulatory Light Chain Interacting Protein (MYLIP))
    Bindungsspezifität
    • 15
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 266-445
    Reaktivität
    • 35
    • 32
    • 23
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 35
    • 2
    Kaninchen
    Klonalität
    • 35
    • 2
    Polyklonal
    Konjugat
    • 18
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MYLIP Antikörper ist unkonjugiert
    Applikation
    • 33
    • 15
    • 13
    • 13
    • 7
    • 5
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Kreuzreaktivität
    Human, Maus
    Aufreinigung
    Antigen Affinity Purified
    Immunogen
    Recombinant Human E3 ubiquitin-protein ligase MYLIP protein (266-445AA)
    Isotyp
    IgG
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  • Applikationshinweise
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    MYLIP (Myosin Regulatory Light Chain Interacting Protein (MYLIP))
    Andere Bezeichnung
    MYLIP (MYLIP Produkte)
    Synonyme
    IDOL antikoerper, MIR antikoerper, 9430057C20Rik antikoerper, Mir antikoerper, mylip antikoerper, wu:fj36b03 antikoerper, zgc:55987 antikoerper, MYLIP antikoerper, mir antikoerper, zgc:153767 antikoerper, myosin regulatory light chain interacting protein antikoerper, myosin regulatory light chain interacting protein a antikoerper, myosin regulatory light chain interacting protein L homeolog antikoerper, myosin regulatory light chain interacting protein b antikoerper, MYLIP antikoerper, Mylip antikoerper, mylipa antikoerper, mylip.L antikoerper, mylip antikoerper, mylipb antikoerper
    Hintergrund

    Background: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC), LDLR, VLDLR and LRP8. Activity depends on E2 enzymes of the UBE2D family. Proteasomal degradation of MRLC leads to inhibit neurite outgrowth in presence of NGF by counteracting the stabilization of MRLC by saposin-like protein (CNPY2/MSAP) and reducing CNPY2-stimulated neurite outgrowth. Acts as a sterol-dependent inhibitor of cellular cholesterol uptake by mediating ubiquitination and subsequent degradation of LDLR.

    Aliases: BM-023 antibody, BZF1 antibody, E3 ubiquitin protein ligase MYLIP antibody, E3 ubiquitin-protein ligase MYLIP antibody, Idol antibody, Inducible degrader of the LDL-receptor antibody, Lipoprotein receptor antibody, MIR antibody, MYLIP antibody, MYLIP_HUMAN antibody, Myosin regulatory light chain interacting protein antibody, PP5242 antibody

    UniProt
    Q8WY64