PIAS3 Antikörper (AA 399-628)

Produktnummer ABIN7150969

Dieses Anti-PIAS3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PIAS3 in IHC und ELISA. Geeignet für Human.

Kurzübersicht für PIAS3 Antikörper (AA 399-628) (ABIN7150969)

Target: PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIAS3 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Produktdetails anti-PIAS3 Antikörper

Bindungsspezifität: AA 399-628

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human E3 SUMO-protein ligase PIAS3 protein (399-628AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PIAS3

Target: PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))

Andere Bezeichnung: PIAS3

Hintergrund:

Background: Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway and the steroid hormone signaling pathway. Involved in regulating STAT3 signaling via inhibiting STAT3 DNA-binding and suppressing cell growth. Enhances the sumoylation of MTA1 and may participate in its paralog-selective sumoylation.

Aliases: E3 SUMO protein ligase PIAS 3 antibody, E3 SUMO protein ligase PIAS3 antibody, E3 SUMO-protein ligase PIAS3 antibody, FLJ14651 antibody, OTTHUMP00000015586 antibody, OTTHUMP00000015587 antibody, PIAS 3 antibody, Pias3 antibody, PIAS3 protein antibody, PIAS3_HUMAN antibody, Protein inhibitor of activated STAT 3 antibody, Protein inhibitor of activated STAT protein 3 antibody, Protein inhibitor of activated STAT3 antibody, Zinc finger MIZ type containing 5 antibody, ZMIZ 5 antibody, ZMIZ5 antibody

UniProt: Q9Y6X2

Pathways: JAK-STAT Signalweg