POLR2G Antikörper (AA 1-172) (Biotin)

Produktnummer ABIN7150439

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch POLR2G in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für POLR2G Antikörper (AA 1-172) (Biotin) (ABIN7150439)

Target: POLR2G (Polymerase (RNA) II (DNA Directed) Polypeptide G (POLR2G))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POLR2G Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-POLR2G Antikörper (Biotin)

Bindungsspezifität: AA 1-172

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human DNA-directed RNA polymerase II subunit RPB7 protein (1-172AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu POLR2G

Target: POLR2G (Polymerase (RNA) II (DNA Directed) Polypeptide G (POLR2G))

Andere Bezeichnung: POLR2G

Hintergrund:

Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB7 is part of a subcomplex with RPB4 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft. The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA (By similarity). Binds RNA.

Aliases: DNA directed RNA polymerase II 19 kDa polypeptide antibody, DNA directed RNA polymerase II subunit G antibody, DNA directed RNA polymerase II subunit RPB7 antibody, DNA-directed RNA polymerase II subunit G antibody, DNA-directed RNA polymerase II subunit RPB7 antibody, hRPB19 antibody, hsRPB7 antibody, MGC138367 antibody, MGC138369 antibody, POLR2G antibody, polymerase (RNA) II (DNA directed) polypeptide G antibody, RNA polymerase II 19 kDa subunit antibody, RNA polymerase II subunit B7 antibody, RPB19 antibody, RPB7 antibody, RPB7_HUMAN antibody

UniProt: P62487

Pathways: Regulatorische RNA Pathways