POLK Antikörper (AA 227-337)
Kurzübersicht für POLK Antikörper (AA 227-337) (ABIN7150255)
Target
Alle POLK Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 227-337
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Kreuzreaktivität
- Human, Maus
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human DNA polymerase kappa protein (227-337AA)
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: WB:1:500-1:5000,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- POLK (Polymerase (DNA Directed) kappa (POLK))
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Andere Bezeichnung
- POLK
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Hintergrund
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Background: DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Depending on the context, it inserts the correct base, but causes frequent base transitions, transversions and frameshifts. Lacks 3\\\'-5\\\' proofreading exonuclease activity. Forms a Schiff base with 5\\\'-deoxyribose phosphate at abasic sites, but does not have lyase activity.
Aliases: DinB homolog 1 (E. coli) antibody, DINB protein antibody, DINB1 antibody, DINP antibody, DNA damage inducible protein b antibody, DNA polymerase kappa antibody, Polk antibody, POLK_HUMAN antibody, POLQ antibody, Polymerase (DNA directed) kappa antibody, polymerase, DNA, kappa antibody
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UniProt
- Q9UBT6
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Pathways
- DNA Reparatur
Target
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