ERCC1 Antikörper (AA 1-323)

Produktnummer ABIN7150168

Dieses Anti-ERCC1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ERCC1 in ELISA, IHC und IF. Geeignet für Human.

Kurzübersicht für ERCC1 Antikörper (AA 1-323) (ABIN7150168)

Target: ERCC1 (Excision Repair Cross Complementing Polypeptide-1 (ERCC1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERCC1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-ERCC1 Antikörper

Bindungsspezifität: AA 1-323

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human DNA excision repair protein ERCC-1 protein (1-323AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ERCC1

Target: ERCC1 (Excision Repair Cross Complementing Polypeptide-1 (ERCC1))

Andere Bezeichnung: ERCC1

Hintergrund:

Background: Isoform 1: Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5\'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4.

Aliases: COFS 4 antibody, COFS4 antibody, DNA excision repair protein ERCC 1 antibody, DNA excision repair protein ERCC-1 antibody, DNA excision repair protein ERCC1 antibody, ERCC 1 antibody, ERCC1 antibody, ERCC1_HUMAN antibody, Excision repair cross complementation group 1 antibody, Excision repair cross complementing 1 antibody, Excision Repair Cross Complementing Rodent Repair Deficiency Complementation Group 1 antibody, Excision repair protein antibody, RAD 10 antibody, RAD10 antibody, UV 20 antibody, UV20 antibody

UniProt: P07992

Pathways: DNA Reparatur, Production of Molecular Mediator of Immune Response