DIS3L2 Antikörper (AA 201-400) (Biotin)
Kurzübersicht für DIS3L2 Antikörper (AA 201-400) (Biotin) (ABIN7150018)
Target
Alle DIS3L2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 201-400
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Kreuzreaktivität
- Human
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human DIS3-like exonuclease 2 protein (201-400AA)
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Isotyp
- IgG
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anti-DIS3-Like Exonuclease 2 (DIS3L2) (AA 27-250) antibody
DIS3L2 Reaktivität: Human WB, ELISA, IHC, FACS Wirt: Maus Monoclonal 6C7B2 unconjugated
anti-DIS3-Like Exonuclease 2 (DIS3L2) (AA 201-400) antibodyDIS3L2 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-DIS3-Like Exonuclease 2 (DIS3L2) (AA 121-170) antibodyDIS3L2 Reaktivität: Human, Maus, Ratte, Hund WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-DIS3-Like Exonuclease 2 (DIS3L2) (N-Term) antibodyDIS3L2 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Schwein WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-DIS3-Like Exonuclease 2 (DIS3L2) (N-Term) antibodyDIS3L2 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-DIS3-Like Exonuclease 2 (DIS3L2) (N-Term) antibodyDIS3L2 Reaktivität: Drosophila melanogaster WB Wirt: Ziege Polyclonal unconjugated
anti-DIS3-Like Exonuclease 2 (DIS3L2) (AA 1-619) antibodyDIS3L2 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-DIS3-Like Exonuclease 2 (DIS3L2) (N-Term) antibodyDIS3L2 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Schwein WB, IHC Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- DIS3L2 (DIS3-Like Exonuclease 2 (DIS3L2))
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Andere Bezeichnung
- DIS3L2
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Hintergrund
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Background: 3\'-5\'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3\' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3\'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mitosis, and negatively regulates cell proliferation.
Aliases: DI3L2_HUMAN antibody, DIS3 L2 antibody, DIS3 mitotic control homolog (S. cerevisiae) like 2 antibody, DIS3 mitotic control homolog like 2 antibody, DIS3-like exonuclease 2 antibody, Dis3l2 antibody, FLJ36974 antibody, MGC42174 antibody
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UniProt
- Q8IYB7
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Pathways
- Stem Cell Maintenance
Target
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