DKK2 Antikörper (AA 34-259)
Kurzübersicht für DKK2 Antikörper (AA 34-259) (ABIN7149882)
Target
Alle DKK2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 34-259
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Kreuzreaktivität
- Human
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human Dickkopf-related protein 2 protein (34-259AA)
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- DKK2 (Dickkopf 2 Homolog (DKK2))
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Andere Bezeichnung
- DKK2
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Hintergrund
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Background: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
Aliases: Dickkopf 2 antibody, Dickkopf gene 2 antibody, Dickkopf homolog 2 antibody, Dickkopf related protein 2 antibody, Dickkopf WNT signaling pathway inhibitor 2 antibody, Dickkopf-2 antibody, Dickkopf-related protein 2 antibody, Dickkopf2 antibody, DKK 2 antibody, Dkk-2 antibody, Dkk2 antibody, DKK2_HUMAN antibody, hDkk 2 antibody, hDkk-2 antibody, hDkk2 antibody
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UniProt
- Q9UBU2
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Pathways
- WNT Signalweg
Target
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