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DPPA3 Antikörper (AA 1-159) (HRP)

Dieses Anti-DPPA3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DPPA3 in ELISA. Geeignet für Human.
Produktnummer ABIN7149823

Kurzübersicht für DPPA3 Antikörper (AA 1-159) (HRP) (ABIN7149823)

Target

Alle DPPA3 Antikörper anzeigen
DPPA3 (Developmental Pluripotency Associated 3 (DPPA3))

Reaktivität

  • 19
  • 12
  • 1
  • 1
Human

Wirt

  • 21
  • 1
Kaninchen

Klonalität

  • 22
Polyklonal

Konjugat

  • 12
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser DPPA3 Antikörper ist konjugiert mit HRP

Applikation

  • 10
  • 6
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
ELISA
  • Bindungsspezifität

    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-159

    Kreuzreaktivität

    Human

    Aufreinigung

    >95%, Protein G purified

    Immunogen

    Recombinant Human Developmental pluripotency-associated protein 3 protein (1-159AA)

    Isotyp

    IgG
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    DPPA3 (Developmental Pluripotency Associated 3 (DPPA3))

    Andere Bezeichnung

    DPPA3

    Hintergrund

    Background: Primordial germ cell (PGCs)-specific protein involved in epigenetic chromatin reprogramming in the zygote following fertilization. In zygotes, DNA demethylation occurs selectively in the paternal pronucleus before the first cell division, while the adjacent maternal pronucleus and certain paternally-imprinted loci are protected from this process. Participates in protection of DNA methylation in the maternal pronucleus by preventing conversion of 5mC to 5hmC: specifically recognizes and binds histone H3 dimethylated at \'Lys-9\' (H3K9me2) on maternal genome, and protects maternal genome from TET3-mediated conversion to 5hmC and subsequent DNA demethylation. Does not bind paternal chromatin, which is mainly packed into protamine and does not contain much H3K9me2 mark. Also protects imprinted loci that are marked with H3K9me2 in mature sperm from DNA demethylation in early embryogenesis. May be important for the totipotent/pluripotent states continuing through preimplantation development. Also involved in chromatin condensation in oocytogenesis (By similarity).

    Aliases: Compaction associated protein 1 antibody, Developmental pluripotency associated 3 antibody, Developmental pluripotency associated protein 3 antibody, Developmental pluripotency-associated protein 3 antibody, Dppa3 antibody, DPPA3_HUMAN antibody, PGC7 antibody, Stella related protein antibody, Stella-related protein antibody

    UniProt

    Q6W0C5
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