DOCK1 Antikörper (AA 1676-1865) (HRP)
Kurzübersicht für DOCK1 Antikörper (AA 1676-1865) (HRP) (ABIN7149582)
Target
Alle DOCK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1676-1865
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Kreuzreaktivität
- Human
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human Dedicator of cytokinesis protein 1 protein (1676-1865AA)
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))
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Andere Bezeichnung
- DOCK1
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Hintergrund
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Background: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen (PubMed:19004829). Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 (PubMed:8657152).
Aliases: 180 kDa protein downstream of CRK antibody, Ced5 antibody, Dedicator of Cytokinesis 1 antibody, Dedicator of cytokinesis protein 1 antibody, DOCK 1 antibody, DOCK 180 antibody, DOCK1 antibody, DOCK1_HUMAN antibody, DOCK180 antibody
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UniProt
- Q14185
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Pathways
- Signaling of Hepatocyte Growth Factor Receptor
Target
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