DAPK2 Antikörper (AA 222-370) (Biotin)

Produktnummer ABIN7149555

Der Kaninchen Polyklonal Anti-DAPK2-Antikörper wurde für ELISA validiert. Er ist geeignet, DAPK2 in Proben von Human zu detektieren.

Kurzübersicht für DAPK2 Antikörper (AA 222-370) (Biotin) (ABIN7149555)

Target: DAPK2 (Death-Associated Protein Kinase 2 (DAPK2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DAPK2 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-DAPK2 Antikörper (Biotin)

Bindungsspezifität: AA 222-370

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Death-associated protein kinase 2 protein (222-370AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu DAPK2

Target: DAPK2 (Death-Associated Protein Kinase 2 (DAPK2))

Andere Bezeichnung: DAPK2

Hintergrund:

Background: Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of malignant epithelial cells. May play a role in granulocytic maturation. Isoform 2 is not regulated by calmodulin. It can phosphorylate MYL9. It can induce membrane blebbing and autophagic cell death.

Aliases: DAK2 antibody, DAP kinase 2 antibody, DAP kinase related protein 1 antibody, DAP kinase related protein 1 beta isoform antibody, DAP-kinase-related protein 1 antibody, DAPK2 antibody, DAPK2_HUMAN antibody, Death associated protein kinase 2 antibody, Death-associated protein kinase 2 antibody, DRP 1 antibody, DRP-1 antibody, DRP1 antibody, MGC119312 antibody

UniProt: Q9UIK4