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DAPK2 Antikörper (N-Term)

DAPK2 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB3053 unconjugated
Produktnummer ABIN1882166
  • Target Alle DAPK2 Antikörper anzeigen
    DAPK2 (Death-Associated Protein Kinase 2 (DAPK2))
    Bindungsspezifität
    • 18
    • 14
    • 7
    • 6
    • 6
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-30, N-Term
    Reaktivität
    • 72
    • 29
    • 13
    • 1
    • 1
    Human, Maus
    Wirt
    • 65
    • 6
    • 1
    Kaninchen
    Klonalität
    • 65
    • 7
    Polyklonal
    Konjugat
    • 34
    • 7
    • 6
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DAPK2 Antikörper ist unkonjugiert
    Applikation
    • 59
    • 43
    • 24
    • 13
    • 13
    • 12
    • 11
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This DAPK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DAPK2.
    Klon
    RB3053
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product DAPK2 Primärantikörper
  • Applikationshinweise
    WB: 1:1000. WB: 1:2000. IHC-P: 1:50~100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Cai, Cao, Zhang, Xue, Zhang, Zhou, Zhou, Sun, Fu: "Oncogenic miR-17/20a Forms a Positive Feed-forward Loop with the p53 Kinase DAPK3 to Promote Tumorigenesis." in: The Journal of biological chemistry, Vol. 290, Issue 32, pp. 19967-75, (2015) (PubMed).

    Karur, Lowell, Besmer, Agosti, Wojchowski: "Lyn kinase promotes erythroblast expansion and late-stage development." in: Blood, Vol. 108, Issue 5, pp. 1524-32, (2006) (PubMed).

    Satoh, Toyota, Itoh, Kikuchi, Obata, Sasaki, Suzuki, Yawata, Kusano, Fujita, Hosokawa, Yanagihara, Tokino, Imai: "DNA methylation and histone deacetylation associated with silencing DAP kinase gene expression in colorectal and gastric cancers." in: British journal of cancer, Vol. 86, Issue 11, pp. 1817-23, (2002) (PubMed).

    Chan, Chan, Tang, Tong, Lo, Lee, Cheung, Wong, Chan, Lai, To: "Hypermethylation of multiple genes in tumor tissues and voided urine in urinary bladder cancer patients." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 8, Issue 2, pp. 464-70, (2002) (PubMed).

    Wong, Chang, Tang, Wei, Kwong, Sham, Yuen, Kwong: "High frequency of promoter hypermethylation of the death-associated protein-kinase gene in nasopharyngeal carcinoma and its detection in the peripheral blood of patients." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 8, Issue 2, pp. 433-7, (2002) (PubMed).

    Shani, Henis-Korenblit, Jona, Gileadi, Eisenstein, Ziv, Admon, Kimchi: "Autophosphorylation restrains the apoptotic activity of DRP-1 kinase by controlling dimerization and calmodulin binding." in: The EMBO journal, Vol. 20, Issue 5, pp. 1099-113, (2001) (PubMed).

  • Target
    DAPK2 (Death-Associated Protein Kinase 2 (DAPK2))
    Andere Bezeichnung
    DAPK2 (DAPK2 Produkte)
    Synonyme
    drp1 antikoerper, drp-1 antikoerper, DAPK2 antikoerper, dapk2 antikoerper, DRP-1 antikoerper, DRP1 antikoerper, death-associated protein kinase 2 L homeolog antikoerper, death associated protein kinase 2 antikoerper, death-associated protein kinase 2b antikoerper, death-associated protein kinase 2 antikoerper, dapk2.L antikoerper, DAPK2 antikoerper, dapk2b antikoerper, dapk2 antikoerper, Dapk2 antikoerper
    Hintergrund
    DAPK2 belongs to the serine/threonine protein kinase family. This protein contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain with significant similarity to that of death-associated protein kinase 1 (DAPK1), a positive regulator of programmed cell death. Overexpression of this gene was shown to induce cell apoptosis. It uses multiple polyadenylation sites.
    Molekulargewicht
    42898
    NCBI Accession
    NP_055141
    UniProt
    Q9UIK4
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