Cytochrome C Antikörper (AA 2-105)
Quick Overview for Cytochrome C Antikörper (AA 2-105) (ABIN7149184)
Target
Alle Cytochrome C (CYCS) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 2-105
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Kreuzreaktivität
- Human, Maus, Ratte
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human Cytochrome c protein (2-105AA)
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))
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Andere Bezeichnung
- CYCS
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Hintergrund
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Background: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.
Aliases: CYC antibody, CYC_HUMAN antibody, CYCS antibody, Cytochrome c antibody, Cytochrome c somatic antibody, HCS antibody, THC4 antibody
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UniProt
- P99999
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Pathways
- Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity
Target
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