ATG4B Antikörper (AA 350-400)

Produktnummer ABIN7149021

Der Kaninchen Polyklonal Anti-ATG4B-Antikörper wurde für WB, ELISA, IHC und IF validiert. Er ist geeignet, ATG4B in Proben von Human zu detektieren.

Kurzübersicht für ATG4B Antikörper (AA 350-400) (ABIN7149021)

Target: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATG4B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-ATG4B Antikörper

Bindungsspezifität: AA 350-400

Kreuzreaktivität: Human, Maus

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Cysteine protease ATG4B protein (350-400AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ATG4B

Target: ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))

Andere Bezeichnung: ATG4B

Hintergrund:

Background: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.

Aliases: APG4 autophagy 4 homolog B antibody, APG4B antibody, ATG4 autophagy related 4 homolog B (S. cerevisiae) antibody, ATG4B antibody, ATG4B_HUMAN antibody, AUT like 1 cysteine endopeptidase antibody, AUT-like 1 cysteine endopeptidase antibody, AUTL1 antibody, Autophagin 1 antibody, Autophagin-1 antibody, Autophagy related 4B cysteine peptidase antibody, Autophagy related cysteine endopeptidase 1 antibody, Autophagy related protein 4 homolog B antibody, Autophagy-related cysteine endopeptidase 1 antibody, Autophagy-related protein 4 homolog B antibody, Cysteine protease ATG4B antibody, hAPG4B antibody, MGC1353 antibody

UniProt: Q9Y4P1

Pathways: Autophagie