CTH Antikörper (AA 1-70)

Produktnummer ABIN7148969

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CTH in WB, IHC, ELISA und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CTH Antikörper (AA 1-70) (ABIN7148969)

Target: CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CTH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-CTH Antikörper

Bindungsspezifität: AA 1-70

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Cystathionine gamma-lyase protein (1-70AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CTH

Target: CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

Andere Bezeichnung: CTH

Hintergrund:

Background: Catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine. Has broad substrate specificity. Converts cystathionine to cysteine, ammonia and 2-oxobutanoate. Converts two cysteine molecules to lanthionine and hydrogen sulfide. Can also accept homocysteine as substrate. Specificity depends on the levels of the endogenous substrates. Generates the endogenous signaling molecule hydrogen sulfide (H2S), and so contributes to the regulation of blood pressure. Acts as a cysteine-protein sulfhydrase by mediating sulfhydration of target proteins: sulfhydration consists of converting -SH groups into -SSH on specific cysteine residues of target proteins such as GAPDH, PTPN1 and NF-kappa-B subunit RELA, thereby regulating their function.

Aliases: CGL_HUMAN antibody, CTH antibody, cystathionase (cystathionine gamma-lyase) antibody, Cystathionine gamma lyase antibody, Cystathionine gamma-lyase antibody, Cysteine desulfhydrase antibody, Gamma cystathionase antibody, Gamma-cystathionase antibody, Homoserine deaminase antibody, Homoserine dehydratase antibody, MGC9471 antibody

UniProt: P32929

Pathways: ER-Nucleus Signaling, Warburg Effekt