C4B Antikörper (AA 1454-1744)

Produktnummer ABIN7148365

Produktdetails anti-C4B Antikörper

Target: C4B (C4b) (Complement Component C4b (C4b))

Bindungsspezifität: AA 1454-1744

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C4B Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Complement C4-B protein (1454-1744AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu C4B

Target: C4B (C4b) (Complement Component C4b (C4b))

Andere Bezeichnung: C4B (C4b Produkte)

Synonyme: C4B1 antikoerper, C4B12 antikoerper, C4B2 antikoerper, C4B3 antikoerper, C4B5 antikoerper, C4BD antikoerper, C4B_2 antikoerper, C4F antikoerper, CH antikoerper, CO4 antikoerper, CPAMD3 antikoerper, C4 antikoerper, C4A2 antikoerper, C4A3 antikoerper, C4A4 antikoerper, C4A6 antikoerper, C4AD antikoerper, C4S antikoerper, CPAMD2 antikoerper, RG antikoerper, wu:fi14a03 antikoerper, C4B antikoerper, DKFZP469I0332 antikoerper, Slp antikoerper, Ss antikoerper, C4-2 antikoerper, C4l antikoerper, complement C4B (Chido blood group) antikoerper, complement C4A (Rodgers blood group) antikoerper, complement component 4 antikoerper, complement C4-B antikoerper, complement component 4B (Chido blood group) antikoerper, complement component 4A (Rodgers blood group) antikoerper, C4B antikoerper, C4A antikoerper, c4 antikoerper, LOC462577 antikoerper, C4a antikoerper, C4b antikoerper

Hintergrund:

Background: Non-enzymatic component of the C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes. C4A isotype is responsible for effective binding to form amide bonds with immune aggregates or protein antigens, while C4B isotype catalyzes the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens. Ref.16 Ref.17 Derived from proteolytic degradation of complement C4, C4a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.

Aliases: Basic complement C4 antibody, C2B5 antibody, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3 antibody, C4b antibody, C4B1 antibody, C4B2 antibody, C4B3 antibody, CO4B_HUMAN antibody, Complement C4 gamma chain antibody, Complement component 4B antibody, CPAMD3 antibody

UniProt: P0C0L5

Pathways: Komplementsystem