IRG1 Antikörper (AA 57-257)

Produktnummer ABIN7147801

Produktdetails anti-IRG1 Antikörper

Target: IRG1 (Immunoresponsive Gene 1 (IRG1))

Bindungsspezifität: AA 57-257

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRG1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Cis-aconitate decarboxylase protein (57-257AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu IRG1

Target: IRG1 (Immunoresponsive Gene 1 (IRG1))

Andere Bezeichnung: ACOD1 (IRG1 Produkte)

Synonyme: CAD antikoerper, AI323667 antikoerper, aconitate decarboxylase 1 antikoerper, ACOD1 antikoerper, Acod1 antikoerper

Hintergrund:

Background: Involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells, ACOD1-mediated itaconic acid production contributes to the antimicrobial activity of macrophages. Plays a role in the embryo implantation.

Aliases: ACOD1 antibody, Aconitate decarboxylase 1 antibody, Aconitate decarboxylase antibody, CAD antibody, Cis aconitate decarboxylase antibody, Immune responsive gene 1 protein homolog antibody, Immune-responsive gene 1 protein homolog antibody, Immunoresponsive 1 homolog (mouse) antibody, Irg1 antibody, IRG1_HUMAN antibody, OC116 antibody, OPTB1 antibody, TCTIRC7 antibody

UniProt: A6NK06