IRG1 Antikörper
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- Target Alle IRG1 Produkte
- IRG1 (Immunoresponsive Gene 1 (IRG1))
- Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser IRG1 Antikörper ist unkonjugiert
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Applikation
- ELISA, Western Blotting (WB)
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Antigen affinity purification
- Immunogen
- Synthetic peptide of human ACOD1
- Isotyp
- IgG
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anti-Immunoresponsive Gene 1 (IRG1) (AA 57-257) antibody
IRG1 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Immunoresponsive Gene 1 (IRG1) (C-Term) antibodyIRG1 Reaktivität: Human ELISA, WB, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB 1:500-1:2000, ELISA 1:5000-1:10000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1.32 mg/mL
- Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- IRG1 (Immunoresponsive Gene 1 (IRG1))
- Andere Bezeichnung
- ACOD1 (IRG1 Produkte)
- Synonyme
- CAD antikoerper, AI323667 antikoerper, aconitate decarboxylase 1 antikoerper, ACOD1 antikoerper, Acod1 antikoerper
- Hintergrund
- Involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells, ACOD1-mediated itaconic acid production contributes to the antimicrobial activity of macrophages. Plays a role in the embryo implantation.
- Molekulargewicht
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Observed_MW: Refer to figures
Calculated_MW: 53 kDa
- UniProt
- A6NK06
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