CHD1 Antikörper (AA 1501-1710)

Produktnummer ABIN7147714

Dieses Anti-CHD1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CHD1 in ELISA, IHC und ChIP. Geeignet für Human.

Kurzübersicht für CHD1 Antikörper (AA 1501-1710) (ABIN7147714)

Target: CHD1 (Chromodomain Helicase DNA Binding Protein 1 (CHD1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHD1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Chromatin Immunoprecipitation (ChIP)

Produktdetails anti-CHD1 Antikörper

Bindungsspezifität: AA 1501-1710

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Chromodomain-helicase-DNA-binding protein 1 protein (1501-1710AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CHD1

Target: CHD1 (Chromodomain Helicase DNA Binding Protein 1 (CHD1))

Andere Bezeichnung: CHD1

Hintergrund:

Background: ATP-dependent chromatin-remodeling factor which functions as substrate recognition component of the transcription regulatory histone acetylation (HAT) complex SAGA. Regulates polymerase II transcription. Also required for efficient transcription by RNA polymerase I, and more specifically the polymerase I transcription termination step. Regulates negatively DNA replication. Not only involved in transcription-related chromatin-remodeling, but also required to maintain a specific chromatin configuration across the genome. Is also associated with histone deacetylase (HDAC) activity (By similarity). Required for the bridging of SNF2, the FACT complex, the PAF complex as well as the U2 snRNP complex to H3K4me3. Functions to modulate the efficiency of pre-mRNA splicing in part through physical bridging of spliceosomal components to H3K4me3. Required for maintaining open chromatin and pluripotency in embryonic stem cells.

Aliases: ATP dependent helicase CHD 1 antibody, ATP-dependent helicase CHD1 antibody, CHD 1 antibody, CHD-1 antibody, Chd1 antibody, CHD1_HUMAN antibody, Chromodomain helicase DNA binding protein 1 antibody, Chromodomain-helicase-DNA-binding protein 1 antibody, DKFZp686E2337 antibody, OTTHUMP00000222625 antibody

UniProt: O14646

Pathways: Chromatin Binding