CBX3 Antikörper (AA 10-122)

Produktnummer ABIN7147701

Der Kaninchen Polyklonal Anti-CBX3-Antikörper wurde für ELISA und IF validiert. Er ist geeignet, CBX3 in Proben von Human zu detektieren.

Kurzübersicht für CBX3 Antikörper (AA 10-122) (ABIN7147701)

Target: CBX3 (Chromobox Homolog 3 (CBX3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CBX3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF)

Produktdetails anti-CBX3 Antikörper

Bindungsspezifität: AA 10-122

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Chromobox protein homolog 3 protein (10-122AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CBX3

Target: CBX3 (Chromobox Homolog 3 (CBX3))

Andere Bezeichnung: CBX3

Hintergrund:

Background: Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at \'Lys-9\', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 \'Lys-9\' trimethylation, mediates the recruitment of the methyltransferases SUV39H1 and/or SUV39H2 by the PER complex to the E-box elements of the circadian target genes such as PER2 itself or PER1.

Aliases: CBX 3 antibody, CBX3 antibody, CBX3_HUMAN antibody, Chromobox homolog 3 (HP1 gamma homolog, Drosophila) antibody, Chromobox homolog 3 antibody, Chromobox protein homolog 3 antibody, GAMMA antibody, HECH antibody, Heterochromatin like protein 1 antibody, Heterochromatin protein 1 homolog gamma antibody, Heterochromatin protein HP1 gamma antibody, HP1 gamma antibody, HP1 gamma homolog antibody, HP1Hs gamma antibody, Modifier 2 protein antibody

UniProt: Q13185