CG1331 Gene Product From Transcript CG1331-RA (CCP84AF) (AA 1-280) Antikörper
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- Target
- CG1331 Gene Product From Transcript CG1331-RA (CCP84AF)
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Bindungsspezifität
- AA 1-280
- Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC)
- Kreuzreaktivität
- Human
- Aufreinigung
- Antigen Affinity Purified
- Immunogen
- Recombinant Human Centriolar coiled-coil protein of 110 kDa protein (1-280AA)
- Isotyp
- IgG
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- Applikationshinweise
- Recommended dilution: IHC:1:20-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- CG1331 Gene Product From Transcript CG1331-RA (CCP84AF)
- Andere Bezeichnung
- CCP11
- Hintergrund
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Background: Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation (PubMed:17719545 PubMed:17681131, PubMed:23486064). Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages (SDA) thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation (By similarity). Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2 (PubMed:16760425).
Aliases: 110 kDa centrosomal protein antibody, CCP110 antibody, Centriolar coiled coil protein 110 kDa antibody, Centrosomal protein 110 kDa antibody, Centrosomal protein CP110 antibody, Centrosomal protein of 110 kDa antibody, Cep110 antibody, CP110 antibody, CP110_HUMAN antibody, DKFZp781G1416 antibody, FAN antibody, KIAA0419 antibody
- UniProt
- O43303
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