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CG1331 Gene Product From Transcript CG1331-RA (CCP84AF) (AA 1-280) Antikörper

CCP84AF Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7147358
  • Target
    CG1331 Gene Product From Transcript CG1331-RA (CCP84AF)
    Bindungsspezifität
    • 1
    • 1
    AA 1-280
    Reaktivität
    Human
    Wirt
    • 2
    Kaninchen
    Klonalität
    • 2
    Polyklonal
    Konjugat
    • 2
    Unkonjugiert
    Applikation
    • 2
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC)
    Kreuzreaktivität
    Human
    Aufreinigung
    Antigen Affinity Purified
    Immunogen
    Recombinant Human Centriolar coiled-coil protein of 110 kDa protein (1-280AA)
    Isotyp
    IgG
  • Applikationshinweise
    Recommended dilution: IHC:1:20-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    CG1331 Gene Product From Transcript CG1331-RA (CCP84AF)
    Andere Bezeichnung
    CCP11
    Hintergrund

    Background: Necessary for centrosome duplication at different stages of procentriole formation. Acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation (PubMed:17719545 PubMed:17681131, PubMed:23486064). Also involved in promoting ciliogenesis. May play a role in the assembly of the mother centriole subdistal appendages (SDA) thereby effecting the fusion of recycling endosomes to basal bodies during cilia formation (By similarity). Required for correct spindle formation and has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CETN2 (PubMed:16760425).

    Aliases: 110 kDa centrosomal protein antibody, CCP110 antibody, Centriolar coiled coil protein 110 kDa antibody, Centrosomal protein 110 kDa antibody, Centrosomal protein CP110 antibody, Centrosomal protein of 110 kDa antibody, Cep110 antibody, CP110 antibody, CP110_HUMAN antibody, DKFZp781G1416 antibody, FAN antibody, KIAA0419 antibody

    UniProt
    O43303
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