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CD44 Antikörper (AA 21-220)

Name: CD44 Antikörper (AA 21-220)
Brand: antibodies-online
SKU: ABIN7147160
Price: 462 EUR
Availability: InStock

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD44 in FACS, WB, IHC, ELISA und IF. Er zeigt eine Reaktivität gegenüber Human.

Western Blot Positive WB detected in: Hela whole cell lysate, HUVEC whole cell lysate, A549 whole cell lysate, MCF-7 whole cell lysate All lanes: CD44 antibody at 1:1500 Secondary Goat polyclonal to Mouse IgG at 1/10000 dilution Predicted band size: 82, 4, 78, 77, 81, 79, 75, 54,47, 40, 44, 33, 74, 76, 38, 16 kDa Observed band size: 95 kDa (CD44 Antikörper (AA 21-220))

Overlay histogram showing Hela cells stained with ABIN7147160 (red line) at 1:200. (CD44 Antikörper (AA 21-220))

FACS

Western Blot Positive WB detected in: A549 whole cell lysate All lanes: CD44 antibody at 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000 Secondary Goat polyclonal to Mouse IgG at 1/10000 dilution Predicted band size: 82, 4, 78, 77, 81, 79, 75, 54,47, 40, 44, 33, 74, 76, 38, 16 kDa Observed band size: 95 kDa (CD44 Antikörper (AA 21-220))

IHC image of ABIN7147160 diluted at 1:100 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. (CD44 Antikörper (AA 21-220))

IHC

IHC image of ABIN7147160 diluted at 1:100 and staining in paraffin-embedded human skin tissue performed on a Leica BondTM system. (CD44 Antikörper (AA 21-220))

IHC

IHC image of ABIN7147160 diluted at 1:100 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. (CD44 Antikörper (AA 21-220))

IHC

Immunofluorescence staining of Hela cells with ABIN7147160 at 1:100, counter-stained with DAPI. (CD44 Antikörper (AA 21-220))

Immunofluorescence staining of MCF-7 cells with ABIN7147160 at 1:100, counter-stained with DAPI. (CD44 Antikörper (AA 21-220))

8 Abbildungen

Produktnummer ABIN7147160

Kurzübersicht für CD44 Antikörper (AA 21-220) (ABIN7147160)

Target

Alle CD44 Antikörper anzeigen

CD44

Reaktivität

Human

Wirt

Maus

Klonalität

Monoklonal

Konjugat

Dieser CD44 Antikörper ist unkonjugiert

Applikation

Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Klon

6G2D2

Discover our top product CD44 Primärantikörper

Bindungsspezifität
16

16

16

11

9

5

4

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 21-220

Kreuzreaktivität

Human

Aufreinigung

Protein G purified

Immunogen

Recombinant Human CD44 antigen protein (21-220AA)

Isotyp

IgG1
anti-CD44 (CD44) antibody
CD44 Reaktivität: Human, Maus FACS, IHC, ELISA, ICC Wirt: Maus Monoclonal 8E2F3 unconjugated

anti-CD44 (CD44) antibody
KO Validated CD44 Reaktivität: Human WB, IF, IHC (p), IP, IHC (fro), ICC, LCI Wirt: Kaninchen Polyclonal unconjugated

anti-CD44 (CD44) antibody
CD44 Reaktivität: Human, Hund, Schwein FACS, WB, IHC (p), IP Wirt: Maus Monoclonal MEM-263 unconjugated

anti-CD44 (CD44) (AA 148-247) antibody
CD44 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-CD44 (CD44) (AA 36-194) antibody
CD44 Reaktivität: Human FACS, WB, IHC, ELISA Wirt: Maus Monoclonal 7F4F1 unconjugated

anti-CD44 (CD44) antibody
CD44 Reaktivität: Human FACS, WB, IHC, ELISA, IHC (p), IP, Inhibition Wirt: Maus Monoclonal MEM-85 unconjugated

anti-CD44 (CD44) (AA 21-259) antibody
CD44 Reaktivität: Human, Maus, Ratte FACS, WB, IHC, ELISA, IF, IHC (fro), ICC Wirt: Kaninchen Polyclonal unconjugated

anti-CD44 (CD44) (AA 35-300) antibody
CD44 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated

anti-CD44 (CD44) (AA 1-361) antibody
CD44 Reaktivität: Human WB, IHC (p) Wirt: Maus Polyclonal unconjugated

anti-CD44 (CD44) antibody
CD44 Reaktivität: Human, Pavian, Green Monkey FACS, WB, IHC, IF, Func, StM Wirt: Maus Monoclonal 156-3C11 unconjugated

Applikationshinweise

Recommended dilution: WB:1:1000-1:40000, IHC:1:50-1:200, IF:1:50-1:200,

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C,-80 °C

Informationen zur Lagerung

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target

CD44

Andere Bezeichnung

CD44

Hintergrund

Background: Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events. Receptor for LGALS9, the interaction enhances binding of SMAD3 to the FOXP3 promoter, leading to up-regulation of FOXP3 expression and increased induced regulatory T (iTreg) cell stability and suppressive function (By similarity).
Aliases: CD44 antigen, CDw44, Epican, Extracellular matrix receptor III, ECMR-III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, Phagocytic glycoprotein 1, PGP-1, Phagocytic glycoprotein I, PGP-I, CD44, CD44, LHR, MDU2, MDU3, MIC4

UniProt

P16070

Pathways

Glycosaminoglycan Metabolic Process, Autophagie, Negative Regulation of intrinsic apoptotic Signaling