CHST14 Antikörper (AA 70-133) (Biotin)

Produktnummer ABIN7146685

Dieses Anti-CHST14-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CHST14 in ELISA. Geeignet für Human.

Kurzübersicht für CHST14 Antikörper (AA 70-133) (Biotin) (ABIN7146685)

Target: CHST14 (Carbohydrate (N-Acetylgalactosamine 4-0) Sulfotransferase 14 (CHST14))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHST14 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-CHST14 Antikörper (Biotin)

Bindungsspezifität: AA 70-133

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Carbohydrate sulfotransferase 14 protein (70-133AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CHST14

Target: CHST14 (Carbohydrate (N-Acetylgalactosamine 4-0) Sulfotransferase 14 (CHST14))

Andere Bezeichnung: CHST14

Hintergrund:

Background: Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of dermatan sulfate. Plays a pivotal role in the formation of 4-0-sulfated IdoA blocks in dermatan sulfate. Transfers sulfate to the C-4 hydroxyl of beta1,4-linked GalNAc that is substituted with an alpha-linked iduronic acid (IdoUA) at the C-3 hydroxyl. Transfers sulfate more efficiently to GalNAc residues in -IdoUA-GalNAc-IdoUA- than in -GlcUA-GalNAc-GlcUA-sequences. Has preference for partially desulfated dermatan sulfate. Addition of sulfate to GalNAc may occur immediately after epimerization of GlcUA to IdoUA. Appears to have an important role in the formation of the cerebellar neural network during postnatal brain development.

Aliases: 2600016L03Rik antibody, ATCS antibody, Carbohydrate (N acetylgalactosamine 4 0) sulfotransferase 14 antibody, Carbohydrate sulfotransferase 14 antibody, CHST14 antibody, CHSTE_HUMAN antibody, D4ST-1 antibody, D4st1 antibody, Dermatan 4-sulfotransferase 1 antibody, hD4ST1 antibody, RP23-286G12.2 antibody, UNQ1925/PRO4400 antibody

UniProt: Q8NCH0

Pathways: Glycosaminoglycan Metabolic Process