KCTD6 Antikörper (AA 1-237) (FITC)
Kurzübersicht für KCTD6 Antikörper (AA 1-237) (FITC) (ABIN7145858)
Target
Alle KCTD6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-237
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Kreuzreaktivität
- Human
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human BTB/POZ domain-containing protein KCTD6 protein (1-237AA)
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Isotyp
- IgG
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anti-Potassium Channel Tetramerisation Domain Containing 6 (KCTD6) (AA 1-237) antibody
KCTD6 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Potassium Channel Tetramerisation Domain Containing 6 (KCTD6) (N-Term) antibodyKCTD6 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Potassium Channel Tetramerisation Domain Containing 6 (KCTD6) (N-Term) antibodyKCTD6 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Potassium Channel Tetramerisation Domain Containing 6 (KCTD6) (AA 1-237) antibodyKCTD6 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Potassium Channel Tetramerisation Domain Containing 6 (KCTD6) (AA 72-121) antibodyKCTD6 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio), Fledermaus, Huhn, Affe, Schwein WB Wirt: Kaninchen Polyclonal unconjugated
anti-Potassium Channel Tetramerisation Domain Containing 6 (KCTD6) (AA 21-70) antibodyKCTD6 Reaktivität: Human WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Potassium Channel Tetramerisation Domain Containing 6 (KCTD6) (N-Term) antibodyKCTD6 Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- KCTD6 (Potassium Channel Tetramerisation Domain Containing 6 (KCTD6))
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Andere Bezeichnung
- KCTD6
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Hintergrund
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Background: Probable substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes the ubiquitination of HDAC1, the function seems to depend on KCTD11:KCTD6 oligomerization. Can function as antagonist of the Hedgehog pathway by affecting the nuclear transfer of transcription factor GLI1, the function probably occurs via HDAC1 down-regulation, keeping GLI1 acetylated and inactive. Inhibits cell growth and tumorigenicity of medulloblastoma (MDB) (PubMed:21472142). Involved in regulating protein levels of ANK1 isoform Mu17 probably implicating CUL3-dependent proteasomal degradation (PubMed:22573887).
Aliases: BTB/POZ domain-containing protein KCTD6 antibody, KCASH3 antibody, kctd6 antibody, KCTD6_HUMAN antibody, MGC27385 antibody, potassium channel tetramerization domain containing 6 antibody
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UniProt
- Q8NC69
Target
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