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BRAP Antikörper (AA 13-124) (HRP)

Dieses Anti-BRAP-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von BRAP in ELISA. Geeignet für Human.
Produktnummer ABIN7145761

Kurzübersicht für BRAP Antikörper (AA 13-124) (HRP) (ABIN7145761)

Target

Alle BRAP Antikörper anzeigen
BRAP (BRCA1 Associated Protein (BRAP))

Reaktivität

  • 25
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 24
  • 1
Kaninchen

Klonalität

  • 24
  • 1
Polyklonal

Konjugat

  • 17
  • 3
  • 2
  • 1
  • 1
  • 1
Dieser BRAP Antikörper ist konjugiert mit HRP

Applikation

  • 19
  • 15
  • 5
  • 4
  • 4
  • 1
  • 1
  • 1
ELISA
  • Bindungsspezifität

    • 9
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 13-124

    Kreuzreaktivität

    Human

    Aufreinigung

    >95%, Protein G purified

    Immunogen

    Recombinant Human BRCA1-associated protein (13-124AA)

    Isotyp

    IgG
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    BRAP (BRCA1 Associated Protein (BRAP))

    Andere Bezeichnung

    BRAP

    Hintergrund

    Background: Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport.

    Aliases: BRAP antibody, RNF52BRCA1-associated protein antibody, EC 2.3.2.27 antibody, BRAP2 antibody, Impedes mitogenic signal propagation antibody, IMP antibody, RING finger protein 52 antibody, RING-type E3 ubiquitin transferase BRAP2 antibody, Renal carcinoma antigen NY-REN-63 antibody

    UniProt

    Q7Z569
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