BRAP Antikörper (AA 13-124) (FITC)

Produktnummer ABIN7145760

Der Kaninchen Polyklonal Anti-BRAP-Antikörper wurde für validiert. Er ist geeignet, BRAP in Proben von Human zu detektieren.

Kurzübersicht für BRAP Antikörper (AA 13-124) (FITC) (ABIN7145760)

Target: BRAP (BRCA1 Associated Protein (BRAP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BRAP Antikörper ist konjugiert mit FITC

Applikation: Bitte anfragen

Produktdetails anti-BRAP Antikörper (FITC)

Bindungsspezifität: AA 13-124

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human BRCA1-associated protein (13-124AA)

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu BRAP

Target: BRAP (BRCA1 Associated Protein (BRAP))

Andere Bezeichnung: BRAP

Hintergrund:

Background: Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto-polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport.

Aliases: BRAP antibody, RNF52BRCA1-associated protein antibody, EC 2.3.2.27 antibody, BRAP2 antibody, Impedes mitogenic signal propagation antibody, IMP antibody, RING finger protein 52 antibody, RING-type E3 ubiquitin transferase BRAP2 antibody, Renal carcinoma antigen NY-REN-63 antibody

UniProt: Q7Z569