BMP1 Antikörper (AA 317-424)
Kurzübersicht für BMP1 Antikörper (AA 317-424) (ABIN7145679)
Target
Alle BMP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 317-424
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Kreuzreaktivität
- Human
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human Bone morphogenetic protein 10 protein (317-424AA)
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: IHC:1:20-1:200,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- BMP1 (Bone Morphogenetic Protein 1 (BMP1))
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Andere Bezeichnung
- BMP1
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Hintergrund
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Background: Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.
Aliases: BMP-10 antibody, Bmp10 antibody, BMP10_HUMAN antibody, Bone morphogenetic protein 10 antibody, Bone morphogenetic protein 10 preproprotein antibody, MGC126783 antibody, OTTHUMP00000159973 antibody
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UniProt
- O95393
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Pathways
- Lipid Metabolism
Target
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