EPRS Antikörper (AA 1207-1399) (Biotin)

Produktnummer ABIN7145567

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch EPRS in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für EPRS Antikörper (AA 1207-1399) (Biotin) (ABIN7145567)

Target: EPRS (Glutamyl-Prolyl-tRNA Synthetase (EPRS))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPRS Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-EPRS Antikörper (Biotin)

Bindungsspezifität: AA 1207-1399

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Bifunctional glutamate/proline--tRNA ligase protein (1207-1399AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu EPRS

Target: EPRS (Glutamyl-Prolyl-tRNA Synthetase (EPRS))

Andere Bezeichnung: EPRS

Hintergrund:

Background: Catalyzes the attachment of the cognate amino acid to the corresponding tRNA in a two-step reaction: the amino acid is first activated by ATP to form a covalent intermediate with AMP and is then transferred to the acceptor end of the cognate tRNA. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the multisynthetase complex and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3\'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.

Aliases: Bifunctional aminoacyl tRNA synthetase antibody, Bifunctional aminoacyl-tRNA synthetase antibody, Bifunctional glutamate/proline tRNA ligase antibody, Cell proliferation-inducing gene 32 protein antibody, DKFZp313B047 antibody, EARS antibody, Eprs antibody, GLNS antibody, Glu pro tRNA synthetase antibody, GLUPRORS antibody, GluRS antibody, Glutamate tRNA ligase antibody, Glutamatyl prolyl tRNA synthetase antibody, Glutaminyl tRNA synthetase antibody, Glutamyl prolyl tRNA synthetase antibody, Glutamyl tRNA synthetase antibody, Glutamyl-tRNA synthetase antibody, PARS antibody, PIG 32 antibody, PIG32 antibody, Proliferation inducing gene 32 protein antibody, Proliferation inducing protein 32 antibody, Proline tRNA ligase antibody, Proline--tRNA ligase antibody, Prolyl tRNA synthetase antibody, Prolyl-tRNA synthetase antibody, QARS antibody, QPRS antibody, SYEP_HUMAN antibody

UniProt: P07814