EPRS Antikörper (AA 651-750)

Produktnummer ABIN1714190

Produktdetails anti-EPRS Antikörper

Target: EPRS (Glutamyl-Prolyl-tRNA Synthetase (EPRS))

Bindungsspezifität: AA 651-750

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPRS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Sheep,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Glutamyl Prolyl tRNA syntase/ProRS

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu EPRS

Target: EPRS (Glutamyl-Prolyl-tRNA Synthetase (EPRS))

Andere Bezeichnung: Glutamyl Prolyl tRNA synthetase/ProRS (EPRS Produkte)

Synonyme: EARS antikoerper, GLUPRORS antikoerper, PARS antikoerper, QARS antikoerper, QPRS antikoerper, wu:fb38d08 antikoerper, wu:ft34d10 antikoerper, 2410081F06Rik antikoerper, 3010002K18Rik antikoerper, C79379 antikoerper, Qprs antikoerper, glutamyl-prolyl-tRNA synthetase antikoerper, glutamyl-prolyl-tRNA synthetase S homeolog antikoerper, EPRS antikoerper, eprs antikoerper, eprs.S antikoerper, Eprs antikoerper

Hintergrund:

Synonyms: EARS, PARS, QARS, QPRS, PIG32, GLUPRORS, Bifunctional glutamate/proline--tRNA ligase, Bifunctional aminoacyl-tRNA synthetase, Cell proliferation-inducing gene 32 protein, Glutamatyl-prolyl-tRNA synthetase, EPRS, GLNS

Background: Catalyzes the attachment of the cognate amino acid to the corresponding tRNA in a two-step reaction: the amino acid is first activated by ATP to form a covalent intermediate with AMP and is then transferred to the acceptor end of the cognate tRNA. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the multisynthetase complex and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.

Gen-ID: 2058

UniProt: P07814