BIM Antikörper (AA 1-198)

Produktnummer ABIN7145302

Dieses Anti-BIM-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von BIM in IHC, ELISA und IF. Geeignet für Human.

Kurzübersicht für BIM Antikörper (AA 1-198) (ABIN7145302)

Target: BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BIM Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-BIM Antikörper

Bindungsspezifität: AA 1-198

Verwendungszweck: BCL2L11 Antibody

Aufreinigung: Protein G purified

Reinheit: >95 %

Immunogen: Recombinant Human Bcl-2-like protein 11 protein (1-198AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu BIM

Target: BIM (BCL2L11) (BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11))

Andere Bezeichnung: BCL2L11

Hintergrund:

Background: Induces apoptosis and anoikis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than isoform BimEL, isoform BimL and isoform BimS. Isoform Bim-gamma induces apoptosis. Isoform Bim-alpha3 induces apoptosis possibly through a caspase-mediated pathway. Isoform BimAC and isoform BimABC lack the ability to induce apoptosis.

Aliases: BCL2 like 11 antibody, B2L11_HUMAN antibody, BAM antibody, Bcl 2 interacting protein Bim antibody, Bcl 2 related ovarian death agonist antibody, Bcl-2-like protein 11 antibody, BCL2 interacting mediator of cell death antibody, BCL2 like 11 (apoptosis facilitator) antibody, BCL2 like protein 11 antibody, Bcl2-interacting mediator of cell death antibody, Bcl2-L-11 antibody, Bcl2l11 antibody, BIM alpha6 antibody, BIM antibody, BIM beta6 antibody, BIM beta7 antibody, BimEL antibody, BimL antibody, BOD antibody

UniProt: O43521

Pathways: PI3K-Akt Signalweg, Neurotrophin Signalübertragung, Tube Formation, Positive Regulation of Endopeptidase Activity