Aurora Kinase C Antikörper (AA 12-143) (FITC)

Produktnummer ABIN7145085

Der Kaninchen Polyklonal Anti-Aurora Kinase C-Antikörper wurde für validiert. Er ist geeignet, Aurora Kinase C in Proben von Human zu detektieren.

Kurzübersicht für Aurora Kinase C Antikörper (AA 12-143) (FITC) (ABIN7145085)

Target: Aurora Kinase C (AURKC)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Aurora Kinase C Antikörper ist konjugiert mit FITC

Applikation: Bitte anfragen

Produktdetails anti-Aurora Kinase C Antikörper (FITC)

Bindungsspezifität: AA 12-143

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Aurora kinase C protein (12-143AA)

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Aurora Kinase C

Target: Aurora Kinase C (AURKC)

Andere Bezeichnung: AURKC

Hintergrund:

Background: Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Plays also a role in meiosis and more particularly in spermatogenesis. Has redundant cellular functions with AURKB and can rescue an AURKB knockdown. Like AURKB, AURKC phosphorylates histone H3 at \'Ser-10\' and \'Ser-28\'. AURKC phosphorylates the CPC complex subunits BIRC5/survivin and INCENP leading to increased AURKC activity. Phosphorylates TACC1, another protein involved in cell division, at \'Ser-228\'.

Aliases: AURKC antibody, AIE 2 antibody, Aie1 antibody, AIE2 antibody, AIK 3 antibody, AIK3 antibody, ARK 3 antibody, ARK-3 antibody, ARK3 antibody, Aur C antibody, AurC antibody, Aurkc antibody, AURKC_HUMAN antibody, aurora 3 antibody, Aurora C antibody, Aurora kinase C antibody, aurora related kinase 3 antibody, Aurora-related kinase 3 antibody, Aurora/Ipl1 related kinase 3 antibody, Aurora/Ipl1-related kinase 3 antibody, Aurora/Ipl1/Eg2 protein 2 antibody, EC 2.7.11.1 antibody, Serine threonine protein kinase 13 antibody, serine/threonine kinase 13 (aurora/IPL1 like) antibody, serine/threonine protein kinase aurora C antibody, Serine/threonine-protein kinase 13 antibody, Serine/threonine-protein kinase aurora-C antibody, SPGF5 antibody, STK13 antibody

UniProt: Q9UQB9

Pathways: Zellzyklus, Maintenance of Protein Location