Aprataxin Antikörper (AA 92-161)

Produktnummer ABIN7144491

Der Kaninchen Polyklonal Anti-Aprataxin-Antikörper wurde für ELISA und IHC validiert. Er ist geeignet, Aprataxin in Proben von Human zu detektieren.

Kurzübersicht für Aprataxin Antikörper (AA 92-161) (ABIN7144491)

Target: Aprataxin (APTX)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Aprataxin Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-Aprataxin Antikörper

Bindungsspezifität: AA 92-161

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Aprataxin protein (92-161AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Aprataxin

Target: Aprataxin (APTX)

Andere Bezeichnung: APTX

Hintergrund:

Background: DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5\'-phosphate termini, resulting in the production of 5\'-phosphate termini that can be efficiently rejoined. Also able to hydrolyze adenosine 5\'-monophosphoramidate (AMP-NH(2)) and diadenosine tetraphosphate (AppppA), but with lower catalytic activity.

Aliases: AOA 1 antibody, AOA antibody, AOA1 antibody, Aprataxin antibody, Aprataxin homolog antibody, Aptx antibody, APTX_HUMAN antibody, Ataxia 1 early onset with hypoalbuminemia antibody, Ataxia1 early onset with hypoalbuminemia antibody, AXA 1 antibody, AXA1 antibody, EAOH antibody, EOAHA antibody, FHA HIT antibody, FHA-HIT antibody, FLJ20157 antibody, Forkhead associated domain histidine triad like antibody, Forkhead associated domain histidine triad like protein antibody, Forkhead-associated domain histidine triad-like protein antibody, MGC1072 antibody

UniProt: Q7Z2E3

Pathways: DNA Reparatur, Chromatin Binding